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    CG10283 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35102, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10283provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032681
    Locus tag
    Dmel_CG10283
    See related
    AllianceGenome:FB:FBgn0032681
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10283
    Summary
    Predicted to enable ubiquitin protein ligase binding activity. Predicted to be located in cytoplasm. Is expressed in dorsal ectoderm anlage; organism; trunk mesoderm anlage; and ventral ectoderm anlage. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 44 and mantle cell lymphoma. Orthologous to human CCDC50 (coiled-coil domain containing 50). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10283 in Genome Data Viewer
    Location:
    36F5-36F5; 2-53 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18472964..18484513, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18472964..18484513, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene let-7 Complex Neighboring gene let-7 Neighboring gene mir-125 stem loop Neighboring gene grindelwald Neighboring gene kon-tiki Neighboring gene UDP-glycosyltransferase family 301 member D1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Sokol NS, et al. Genes Dev, 2008 Jun 15. PMID 18559475, Free PMC Article
    2. The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila. Schnorrer F, et al. Dev Cell, 2007 May. PMID 17488626
    3. The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F. Bugga L, et al. Mol Cell Biol, 2009 Jun. PMID 19332563, Free PMC Article
    4. The cis-regulatory code of Hox function in Drosophila. Sorge S, et al. EMBO J, 2012 Aug 1. PMID 22781127, Free PMC Article
    5. Integrative genomic analysis reveals novel regulatory mechanisms of eyeless during Drosophila eye development. Yeung K, et al. Nucleic Acids Res, 2018 Dec 14. PMID 30295802, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10283-PA
    CG10283-PB
    CG10283-PC
    CG10283-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18472964..18484513 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169536.3 → NP_001163007.1  uncharacterized protein Dmel_CG10283, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163007.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JHK9, M9WDW9
      Conserved Domains (2) summary
      cl02600
      Location:440 → 497
      HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
      cl23720
      Location:14 → 132
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    2. NM_001169535.3 → NP_001163006.1  uncharacterized protein Dmel_CG10283, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163006.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JHK9, M9WDW9
      Conserved Domains (2) summary
      cl02600
      Location:440 → 497
      HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
      cl23720
      Location:14 → 132
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    3. NM_165255.4 → NP_724113.1  uncharacterized protein Dmel_CG10283, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724113.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9WDW9, Q9VJ84
      Related
      FBpp0080636
      Conserved Domains (2) summary
      cl02600
      Location:440 → 491
      HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
      cl23720
      Location:14 → 132
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    4. NM_136035.7 → NP_609879.1  uncharacterized protein Dmel_CG10283, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609879.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9WDW9, Q9VJ84
      Related
      FBpp0080635
      Conserved Domains (2) summary
      cl02600
      Location:440 → 491
      HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
      cl23720
      Location:14 → 132
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JHK9 E1JHK9
    Q5BHX9 Q5BHX9
    Q95RA6 Q95RA6
    Q9VJ84 Q9VJ84

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