Scarf1 scavenger receptor class F, member 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Scarf1provided by RGD
Official Full Name: scavenger receptor class F, member 1provided by RGD
Primary source: RGD:1309330
See related: EnsemblRapid:ENSRNOG00000059618 AllianceGenome:RGD:1309330
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable low-density lipoprotein particle binding activity and scavenger receptor activity. Predicted to be involved in neuron remodeling and positive regulation of axon regeneration. Predicted to act upstream of or within dendrite development. Predicted to be located in membrane. Orthologous to human SCARF1 (scavenger receptor class F member 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Lung (RPKM 107.9), Heart (RPKM 98.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q24

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (60857494..60869795)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (60359213..60371516)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (63662967..63683916)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
Title: SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
LncRNA BC088259 promotes Schwann cell migration through Vimentin following peripheral nerve injury.
Title: LncRNA BC088259 promotes Schwann cell migration through Vimentin following peripheral nerve injury.

Submit: New GeneRIF Correction

General gene information

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Markers

RH139395 (e-PCR)
- UniSTS:221481

RH131977 (e-PCR)
- UniSTS:215260

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables low-density lipoprotein particle binding	IBA Inferred from Biological aspect of Ancestor more info
enables low-density lipoprotein particle binding	ISO Inferred from Sequence Orthology more info
enables scavenger receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables scavenger receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in dendrite development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within dendrite development	ISO Inferred from Sequence Orthology more info
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuron remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in neuron remodeling	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of axon regeneration	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of neuron projection development	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of neuron projection development	ISO Inferred from Sequence Orthology more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: scavenger receptor class F member 1

Names: endothelial cells scavenger receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.