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    Nalf1 NALCN channel auxiliary factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498667, updated on 27-Dec-2024

    Summary

    Symbol
    Nalf1provided by RGD
    Full Name
    NALCN channel auxiliary factor 1provided by RGD
    Primary source
    RGD:1559498
    See related
    EnsemblRapid:ENSRNOG00000066120 AllianceGenome:RGD:1559498
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem28; Fam155a; RGD1559498
    Summary
    Predicted to contribute to stretch-activated, monoatomic cation-selective, calcium channel activity. Predicted to be involved in calcium ion import across plasma membrane. Predicted to be active in plasma membrane. Orthologous to human NALF1 (NALCN channel auxiliary factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 168.7) See more
    Orthologs
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    Genomic context

    See Nalf1 in Genome Data Viewer
    Location:
    16q12.5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (86415540..86938150)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (79713577..80236295)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (85528126..86053447)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097573 Neighboring gene ribosomal protein S23, pseudogene 10 Neighboring gene uncharacterized LOC134482427 Neighboring gene uncharacterized LOC120097419 Neighboring gene uncharacterized LOC134482426 Neighboring gene solute carrier family 25 member 5, pseudogene 1 Neighboring gene uncharacterized LOC102546303

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to stretch-activated, monoatomic cation-selective, calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in calcium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NALCN channel auxiliary factor 1
    Names
    family with sequence similarity 155, member A
    transmembrane protein 28
    transmembrane protein FAM155A
    transmembrane protein FAM155A-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402488.1NP_001389417.1  NALCN channel auxiliary factor 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A0A8I5ZWL6
      Related
      ENSRNOP00000083842.1, ENSRNOT00000109798.2
    2. NM_001402489.1NP_001389418.1  NALCN channel auxiliary factor 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/TrEMBL
      A0A8I5ZZY6, A6IWS4
      Related
      ENSRNOP00000084738.1, ENSRNOT00000115375.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      86415540..86938150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)