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    wdn wings down [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43398, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wdnprovided by FlyBase
    Official Full Name
    wings downprovided by FlyBase
    Primary source
    FLYBASE:FBgn0005642
    Locus tag
    Dmel_CG1454
    See related
    AllianceGenome:FB:FBgn0005642
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1454; Dmel\CG1454; pqp; sry h-l; sry-c; sry-h1; Sryc
    Summary
    Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including antennal primordium; embryonic/larval midgut primordium; female germline cell; ganglia; and head epidermis primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See wdn in Genome Data Viewer
    Location:
    98E5-98E5; 3-97 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28807983..28811337, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24633705..24637059, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene intrepid Neighboring gene Chemosensory protein A 98a Neighboring gene ncRNA Neighboring gene pre-mRNA processing factor 39 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. sry h-1, a new Drosophila melanogaster multifingered protein gene showing maternal and zygotic expression. Vincent A, et al. Mol Cell Biol, 1988 Oct. PMID 3141791, Free PMC Article
    2. The Drosophila pourquoi-pas?/wings-down zinc finger protein: oocyte nucleus localization and embryonic requirement. Ségalat L, et al. Genes Dev, 1992 Jun. PMID 1592256
    3. Dissection of the Drosophila pourquoi-pas? promoter: complex ovarian expression is driven by distinct follicle cell- and germ line-specific enhancers. Ségalat L, et al. Mech Dev, 1994 Sep. PMID 7848871
    4. Intercellular cytoplasm transport during Drosophila oogenesis. Mahajan-Miklos S, et al. Dev Biol, 1994 Oct. PMID 7958404
    5. New Drosophila Long-Term Memory Genes Revealed by Assessing Computational Function Prediction Methods. Kacsoh BZ, et al. G3 (Bethesda), 2019 Jan 9. PMID 30463884, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    wings down
    Names
    CG1454-PA
    pourquoi-pas
    serendipity cognate
    serendipity-cognate
    wdn-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      28807983..28811337 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057552.4 → NP_476900.1  wings down [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476900.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P15619, Q9VAT4
      Related
      FBpp0084725
      Conserved Domains (4) summary
      COG1594
      Location:333 → 425
      RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
      sd00017
      Location:360 → 380
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:358 → 380
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:372 → 395
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P15619.2 P15619

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