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    CG8441 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36792, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8441provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034086
    Locus tag
    Dmel_CG8441
    See related
    AllianceGenome:FB:FBgn0034086
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8441
    Summary
    Predicted to enable double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Predicted to be active in nucleolus. Is expressed in organism. Orthologous to human PRKRIP1 (PRKR interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8441 in Genome Data Viewer
    Location:
    52F5-52F5; 2-78 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16185122..16186506, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12072627..12074011, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Protein tyrosine phosphatase 52F Neighboring gene Lissencephaly-1 Neighboring gene clueless Neighboring gene calypso Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Vivo RNAi-Based Screens: Studies in Model Organisms. Yamamoto-Hino M, et al. Genes (Basel), 2013 Nov 25. PMID 24705267, Free PMC Article
    2. A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila. Aikin R, et al. PLoS One, 2012. PMID 22432040, Free PMC Article
    3. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
    4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables double-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8441-PA
    CG8441-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16185122..16186506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259433.1 → NP_001246362.1  uncharacterized protein Dmel_CG8441, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246362.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1V1
      Conserved Domains (1) summary
      pfam06658
      Location:58 → 194
      DUF1168; Protein of unknown function (DUF1168)

    2. NM_137250.4 → NP_611094.1  uncharacterized protein Dmel_CG8441, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611094.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K1V1
      Related
      FBpp0086385
      Conserved Domains (1) summary
      pfam06658
      Location:58 → 194
      DUF1168; Protein of unknown function (DUF1168)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K1V1 Q7K1V1

    Gene LinkOut

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