U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    tyf twenty-four [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31363, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    tyfprovided by FlyBase
    Official Full Name
    twenty-fourprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026083
    Locus tag
    Dmel_CG4857
    See related
    AllianceGenome:FB:FBgn0026083
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG485; CG4857; Dmel\CG4857; EG:EG0007.12; EG:EG0007.4; TYF
    Summary
    Involved in defense response to bacterium; locomotor rhythm; and positive regulation of translation. Predicted to be active in cytoplasm and nucleus. Is expressed in embryonic brain and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See tyf in Genome Data Viewer
    Location:
    4B1-4B1; 1-7 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (4117020..4130016)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (4011053..4024049)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ciboulot Neighboring gene NOP2-Sun domain family, member 2 Neighboring gene Tat interactive protein 60kDa Neighboring gene dim gamma-tubulin 4 Neighboring gene Glucuronyltransferase I Neighboring gene Fasciclin 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Effects of different per translational kinetics on the dynamics of a core circadian clock model. Nieto PS, et al. PLoS One, 2015. PMID 25607544, Free PMC Article
    2. Ataxin2 functions via CrebA to mediate Huntingtin toxicity in circadian clock neurons. Xu F, et al. PLoS Genet, 2019 Oct. PMID 31593562, Free PMC Article
    3. Ataxin-2, Twenty-four, and Dicer-2 are components of a noncanonical cytoplasmic polyadenylation complex. Nadimpalli HP, et al. Life Sci Alliance, 2022 Sep 16. PMID 36114004, Free PMC Article
    4. A role for Drosophila ATX2 in activation of PER translation and circadian behavior. Zhang Y, et al. Science, 2013 May 17. PMID 23687048, Free PMC Article
    5. The novel gene twenty-four defines a critical translational step in the Drosophila clock. Lim C, et al. Nature, 2011 Feb 17. PMID 21331043, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    mobile_element

    • Loc: 4128176-4128575 mobile_element_type = transposon:INE-1{}2001

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in locomotor rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    twenty-four
    Names
    CG4857-PB
    CG4857-PC
    CG4857-PF
    CG4857-PG
    CG4857-PH
    CG4857-PI
    CG4857-PJ
    CG4857-PK
    CG4857-PL
    CG4857-PM
    CG4857-PN
    TWENTY-FOUR
    twenty four
    tyf-PB
    tyf-PC
    tyf-PF
    tyf-PG
    tyf-PH
    tyf-PI
    tyf-PJ
    tyf-PK
    tyf-PL
    tyf-PM
    tyf-PN

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      4117020..4130016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169186.2 → NP_001162657.1  twenty-four, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162657.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD4, O97423, O97424, Q9W4M7
      Conserved Domains (1) summary
      cl01868
      Location:1546 → 1622
      YukC; WXG100 protein secretion system (Wss), protein YukC

    2. NM_131924.3 → NP_572152.2  twenty-four, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572152.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD4, O97423, O97424, Q9W4M7
      Related
      FBpp0070611
      Conserved Domains (1) summary
      cl01868
      Location:1546 → 1622
      YukC; WXG100 protein secretion system (Wss), protein YukC

    3. NM_001169187.2 → NP_001162658.2  twenty-four, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162658.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD4, O97423, O97424, Q9W4M7
      Conserved Domains (1) summary
      cl01868
      Location:1546 → 1622
      YukC; WXG100 protein secretion system (Wss), protein YukC

    4. NM_001297924.2 → NP_001284853.1  twenty-four, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284853.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD4, O97423, O97424, Q9W4M7
      Conserved Domains (1) summary
      cl01868
      Location:1546 → 1622
      YukC; WXG100 protein secretion system (Wss), protein YukC

    5. NM_001258590.2 → NP_001245519.1  twenty-four, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245519.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD4, O97423, O97424, Q9W4M7
      Conserved Domains (1) summary
      cl01868
      Location:1546 → 1622
      YukC; WXG100 protein secretion system (Wss), protein YukC

    6. NM_001258591.2 → NP_001245520.1  twenty-four, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245520.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD6, E1JJD7
      Conserved Domains (1) summary
      cl01868
      Location:1302 → 1378
      YukC; WXG100 protein secretion system (Wss), protein YukC

    7. NM_001169189.3 → NP_001162660.1  twenty-four, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162660.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD6, E1JJD7
      Conserved Domains (1) summary
      cl01868
      Location:1302 → 1378
      YukC; WXG100 protein secretion system (Wss), protein YukC

    8. NM_001258592.2 → NP_001245521.1  twenty-four, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245521.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD6, E1JJD7
      Conserved Domains (1) summary
      cl01868
      Location:1302 → 1378
      YukC; WXG100 protein secretion system (Wss), protein YukC

    9. NM_001258589.2 → NP_001245518.1  twenty-four, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245518.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD6, E1JJD7
      Conserved Domains (1) summary
      cl01868
      Location:1302 → 1378
      YukC; WXG100 protein secretion system (Wss), protein YukC

    10. NM_001258588.2 → NP_001245517.1  twenty-four, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245517.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD6, E1JJD7
      Conserved Domains (1) summary
      cl01868
      Location:1302 → 1378
      YukC; WXG100 protein secretion system (Wss), protein YukC

    11. NM_001169188.3 → NP_001162659.2  twenty-four, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162659.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJD6, E1JJD7
      Conserved Domains (1) summary
      cl01868
      Location:1302 → 1378
      YukC; WXG100 protein secretion system (Wss), protein YukC
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JJD6 E1JJD6
    Q7K764 Q7K764
    Q7K765 Q7K765
    Q8MSV7 Q8MSV7
    Q95RH4 Q95RH4
    Q9W4M7 Q9W4M7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools