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    CG6712 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34631, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6712provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032408
    Locus tag
    Dmel_CG6712
    See related
    AllianceGenome:FB:FBgn0032408
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6712; ORF2
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in neuroblasts; nurse cell; organism; ovary; and presumptive embryonic/larval digestive system. Orthologous to human RPF1 (ribosome production factor 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6712 in Genome Data Viewer
    Location:
    33C4-33C4; 2-46 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12095176..12096511, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12095176..12096511, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44593 Neighboring gene long non-coding RNA:CR44594 Neighboring gene Peroxin 19 Neighboring gene Methyltransferase 2 Neighboring gene Ced-12 Neighboring gene patsas

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries. Lyko F, et al. Mech Dev, 2000 Jul. PMID 10906465
    2. The archaeal homolog of the Imp4 protein, a eukaryotic U3 snoRNP component. Mayer C, et al. Trends Biochem Sci, 2001 Mar. PMID 11246005
    3. The eukaryotic DNMT2 genes encode a new class of cytosine-5 DNA methyltransferases. Tang LY, et al. J Biol Chem, 2003 Sep 5. PMID 12819212
    4. PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. Ciurciu A, et al. PLoS Genet, 2013 Oct. PMID 24204300, Free PMC Article
    5. A genome-wide RNAi screen reveals multiple regulators of caspase activation. Yi CH, et al. J Cell Biol, 2007 Nov 19. PMID 17998402, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables rRNA primary transcript binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of 5.8S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6712-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12095176..12096511 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058131.5 → NP_477479.1  uncharacterized protein Dmel_CG6712 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477479.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VKB4
      Related
      FBpp0079946
      Conserved Domains (1) summary
      smart00879
      Location:188 → 358
      Brix; The Brix domain is found in a number of eukaryotic proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKB4.1 Q9VKB4

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