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    sds22 sds22 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42091, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sds22provided by FlyBase
    Official Full Name
    sds22provided by FlyBase
    Primary source
    FLYBASE:FBgn0028992
    Locus tag
    Dmel_CG5851
    See related
    AllianceGenome:FB:FBgn0028992
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5851; CT18355; Dmel\CG5851; Sds22
    Summary
    Involved in establishment or maintenance of polarity of follicular epithelium; establishment or maintenance of polarity of larval imaginal disc epithelium; and negative regulation of cell population proliferation. Located in apical part of cell and cytoplasm. Is expressed in adult head and organism. Orthologous to human PPP1R7 (protein phosphatase 1 regulatory subunit 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sds22 in Genome Data Viewer
    Location:
    90A5-90A5; 3-60 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17391594..17393020)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13217316..13218742)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44256 Neighboring gene Brf RNA polymerase III subunit Neighboring gene long non-coding RNA:CR43196 Neighboring gene lute Neighboring gene antisense RNA:CR44160 Neighboring gene Cellular Repressor of E1A-stimulated Genes Neighboring gene Sur-8 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in establishment or maintenance of polarity of follicular epithelium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment or maintenance of polarity of larval imaginal disc epithelium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical part of cell IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sds22
    Names
    CG5851-PA
    sds22-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      17391594..17393020
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142362.4 → NP_650619.1  sds22 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650619.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U3W5, Q9VEK8
      Related
      FBpp0082877
      Conserved Domains (3) summary
      sd00033
      Location:43 → 62
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:83 → 125
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:61 → 117
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U3W5 Q9U3W5
    Q9VEK8 Q9VEK8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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