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    Eglp1 Entomoglyceroporin 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37736, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Eglp1provided by FlyBase
    Official Full Name
    Entomoglyceroporin 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0034882
    Locus tag
    Dmel_CG5398
    See related
    AllianceGenome:FB:FBgn0034882
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.151; Aqp5398; CG5398; Dmel\CG5398; Eglp 1
    Summary
    Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to human AQP6 (aquaporin 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Eglp1 in Genome Data Viewer
    Location:
    59F4-59F4; 2-104 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23602585..23603641)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19490108..19491164)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Immune induced molecule 18 Neighboring gene uncharacterized protein Neighboring gene Entomoglyceroporin 2 Neighboring gene Entomoglyceroporin 3 Neighboring gene Entomoglyceroporin 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin. Kaufmann N, et al. Am J Physiol Cell Physiol, 2005 Aug. PMID 15800049
    2. Insect glycerol transporters evolved by functional co-option and gene replacement. Finn RN, et al. Nat Commun, 2015 Jul 17. PMID 26183829, Free PMC Article
    3. Genetic mapping with SNP markers in Drosophila. Berger J, et al. Nat Genet, 2001 Dec. PMID 11726933
    4. Computational identification of Ftz/Ftz-F1 downstream target genes. Bowler T, et al. Dev Biol, 2006 Nov 1. PMID 16996052
    5. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Jin W, et al. Nat Genet, 2001 Dec. PMID 11726925

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    entomoglyceroporin 1
    Names
    CG5398-PA
    Eglp1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23602585..23603641
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137966.2 → NP_611810.1  entomoglyceroporin 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611810.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1M4
      Related
      FBpp0071980, FBtr0072071
      Conserved Domains (1) summary
      cl00200
      Location:13 → 223
      MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1M4 Q9W1M4

    Gene LinkOut

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