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    Cpr11B Cuticular protein 11B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32203, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cpr11Bprovided by FlyBase
    Official Full Name
    Cuticular protein 11Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030398
    Locus tag
    Dmel_CG2555
    See related
    AllianceGenome:FB:FBgn0030398
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2555; DmelCpr11B; Dmel\CG2555
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. Is expressed in embryonic ventral epidermis and larval foregut atrium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cpr11B in Genome Data Viewer
    Location:
    11B1-11B1; 1-39 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12553124..12554235)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (12447157..12448268)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Meckel syndrome, type 1 Neighboring gene meduse Neighboring gene heavyweight Neighboring gene Protein interacting with Ttk69 and Sin3A Neighboring gene LIM domain kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: expression and predicted prohormone processing. Taylor CA, et al. J Neurobiol, 2004 Feb 15. PMID 14750150
    2. A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome. Ren J, et al. Hum Mol Genet, 2011 Sep 1. PMID 21653638, Free PMC Article
    3. The neuropeptide Drosulfakinin regulates social isolation-induced aggression in Drosophila. Agrawal P, et al. J Exp Biol, 2020 Jan 29. PMID 31900346, Free PMC Article
    4. Sensitivity of the distribution of mutational fitness effects to environment, genetic background, and adaptedness: a case study with Drosophila. Wang AD, et al. Evolution, 2014 Mar. PMID 24206451
    5. A Hopscotch-chromatin connection. Betz A, et al. Nat Genet, 2006 Sep. PMID 16941005

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cuticular protein 11B
    Names
    CG2555-PA
    CG2555-PB
    Cpr11B-PA
    Cpr11B-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12553124..12554235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132579.3 → NP_572807.1  cuticular protein 11B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572807.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B4F5X8, C0MLV9, Q9VYM0
      Related
      FBpp0073486
      Conserved Domains (1) summary
      pfam00379
      Location:85 → 139
      Chitin_bind_4; Insect cuticle protein

    2. NM_001272556.1 → NP_001259485.1  cuticular protein 11B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259485.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B4F5X8, M9PGZ2
      Conserved Domains (1) summary
      pfam00379
      Location:85 → 139
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PGZ2 M9PGZ2
    Q9VYM0 Q9VYM0

    Gene LinkOut

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