U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG10126 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41579, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG10126provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038088
    Locus tag
    Dmel_CG10126
    See related
    AllianceGenome:FB:FBgn0038088
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT28495; Dmel\CG10126
    Summary
    Predicted to enable calcium ion binding activity. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic head epidermis; embryonic ventral epidermis; and embryonic/larval posterior spiracle. Orthologous to several human genes including CAPSL (calcyphosine like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG10126 in Genome Data Viewer
    Location:
    87D2-87D2; 3-53 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12855544..12859246, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8681266..8684968, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45587 Neighboring gene long non-coding RNA:CR44234 Neighboring gene long non-coding RNA:CR46218 Neighboring gene antisense RNA:CR44235 Neighboring gene davis-cup

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Jansen IE, et al. Genome Biol, 2017 Jan 30. PMID 28137300, Free PMC Article
    2. A hormonal cue promotes timely follicle cell migration by modulating transcription profiles. Manning L, et al. Mech Dev, 2017 Dec. PMID 28610887, Free PMC Article
    3. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article
    4. RNA degradation is required for the germ-cell to maternal transition in Drosophila. Blatt P, et al. Curr Biol, 2021 Jul 26. PMID 33989522, Free PMC Article
    5. The transcriptional diversity of 25 Drosophila cell lines. Cherbas L, et al. Genome Res, 2011 Feb. PMID 21177962, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG10126-PA
    CG10126-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12855544..12859246 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176487.2 → NP_788664.2  uncharacterized protein Dmel_CG10126, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788664.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86PF4
      Related
      FBpp0082155
      Conserved Domains (2) summary
      cd00051
      Location:64 → 119
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:62 → 119
      EF-hand_7; EF-hand domain pair

    2. NM_141977.3 → NP_650234.3  uncharacterized protein Dmel_CG10126, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650234.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95SJ0, Q9VG23
      Related
      FBpp0082154
      Conserved Domains (2) summary
      cd00051
      Location:52 → 107
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:50 → 107
      EF-hand_7; EF-hand domain pair
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86PF4 Q86PF4
    Q9VG23 Q9VG23

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools