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    CG3270 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35575, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3270provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033093
    Locus tag
    Dmel_CG3270
    See related
    AllianceGenome:FB:FBgn0033093
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3270
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be active in cytoplasm. Is expressed in adult head. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 19. Orthologous to human FOXRED1 (FAD dependent oxidoreductase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3270 in Genome Data Viewer
    Location:
    42C5-42C5; 2-55 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6693430..6695187)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2580935..2582692)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ribonuclease P/MRP subunit p25 Neighboring gene antisense RNA:CR44165 Neighboring gene uncharacterized protein Neighboring gene Tyrosine decarboxylase 2 Neighboring gene MOB kinase activator 4 Neighboring gene Rab2 Neighboring gene uncharacterized protein Neighboring gene chaski Neighboring gene mir-4975 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. Schulte J, et al. J Neurosci, 2010 Apr 14. PMID 20392941, Free PMC Article
    2. Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study. Cuesta-Astroz Y, et al. Front Genet, 2021. PMID 34394179, Free PMC Article
    3. Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster. Gao N, et al. Cell Death Differ, 2022 Dec. PMID 35840760, Free PMC Article
    4. The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment. Qu S, et al. Mol Psychiatry, 2024 Jan. PMID 37957291, Free PMC Article
    5. Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis. Zhou J, et al. Sci Adv, 2019 Sep. PMID 31555733, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex I assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial respiratory chain complex I assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3270-PA
    NP_610228.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6693430..6695187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136384.3 → NP_610228.1  uncharacterized protein Dmel_CG3270 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610228.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6N5, A8WHM4
      Related
      FBpp0085457
      Conserved Domains (1) summary
      COG0665
      Location:54 → 432
      DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z6N5 A1Z6N5
    Q95U69 Q95U69

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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