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    CG12848 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50139, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12848provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040666
    Locus tag
    Dmel_CG12848
    See related
    AllianceGenome:FB:FBgn0040666
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12848
    Summary
    Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrial ribosome. Predicted to be active in mitochondrion and nucleoplasm. Is expressed in adult head. Orthologous to human CHCHD1 (coiled-coil-helix-coiled-coil-helix domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12848 in Genome Data Viewer
    Location:
    60E1-60E1; 2-107 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24762566..24763094, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20650089..20650617, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ubiquitin specific protease 15/31 Neighboring gene spatzle 6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glutathione S transferase E12 Neighboring gene Epidermal growth factor receptor pathway substrate clone 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Shared enhancer gene regulatory networks between wound and oncogenic programs. Floc'hlay S, et al. Elife, 2023 May 3. PMID 37133250, Free PMC Article
    2. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    3. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in mitochondrial translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12848-PA
    CG12848-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24762566..24763094 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144050.3 → NP_652307.1  uncharacterized protein Dmel_CG12848, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652307.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W114
      Related
      FBpp0072342
      Conserved Domains (1) summary
      pfam06747
      Location:47 → 81
      CHCH; CHCH domain

    2. NM_001274242.2 → NP_001261171.1  uncharacterized protein Dmel_CG12848, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261171.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W114
      Conserved Domains (1) summary
      pfam06747
      Location:47 → 81
      CHCH; CHCH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W114 Q9W114

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