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    Ubc87F Ubiquitin conjugating enzyme 87F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41682, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ubc87Fprovided by FlyBase
    Official Full Name
    Ubiquitin conjugating enzyme 87Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0267383
    Locus tag
    Dmel_CG9602
    See related
    AllianceGenome:FB:FBgn0267383
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    83A; AT76; BcDNA:GH25305; CG9602; Dmel\CG9602; UBC; Ubc87Fb; Ube2G1
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Orthologous to human UBE2G1 (ubiquitin conjugating enzyme E2 G1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ubc87F in Genome Data Viewer
    Location:
    87F12-87F12; 3-54 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13717454..13718176, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9543176..9543898, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR34044 Neighboring gene primo-1 Neighboring gene primo-2 Neighboring gene kramer Neighboring gene uncharacterized protein Neighboring gene Chitinase 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila primo locus encodes two low-molecular-weight tyrosine phosphatases. Miller DT, et al. Gene, 2000 Feb 8. PMID 10675607
    2. UbcD4, an ortholog of E2-25K/Ube2K, is essential for activation of the immune deficiency pathway in Drosophila. Park ES, et al. Biochem Biophys Res Commun, 2016 Jan 22. PMID 26707646
    3. Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins. Jones D, et al. Genome Biol, 2002. PMID 11806825, Free PMC Article
    4. What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor? Michelle C, et al. J Mol Evol, 2009 Jun. PMID 19452197, Free PMC Article
    5. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin conjugating enzyme 87F
    Names
    CG9602-PA
    Ubc87F-PA
    ubiquitin conjugating enzyme 87Fb
    NP_650309.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13717454..13718176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142052.2 → NP_650309.1  ubiquitin conjugating enzyme 87F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650309.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IH42, Q9VFR8
      Related
      FBpp0082303
      Conserved Domains (2) summary
      COG5078
      Location:1 → 163
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      pfam00179
      Location:10 → 160
      UQ_con; Ubiquitin-conjugating enzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IH42 Q8IH42
    Q9VFR8 Q9VFR8

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