CG44837 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG44837provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0266100
Locus tag: Dmel_CG44837
See related: AllianceGenome:FB:FBgn0266100
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG14126; CG14129; CG34420; CG5917; Dmel\CG44837
Old locus tag: CG14129; CG5917; Dmel_CG14126; Dmel_CG14129; Dmel_CG34420; Dmel_CG5917
Summary: Predicted to enable metallodipeptidase activity. Predicted to be involved in proteolysis. Is expressed in adult head. Orthologous to human DPEP2 (dipeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 68E2-68E3; 3-37 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (11850645..11938872, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (11843745..11931972, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

mobile_element

Loc: c11865846-11864607 mobile_element_type = transposon:pogo{}985

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables metallodipeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG44837-PB; CG44837-PC; CG44837-PD; rugose

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_037436.4 Reference assembly

Range

11850645..11938872 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001300108.1 → NP_001287037.1 uncharacterized protein Dmel_CG44837, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001287037.1

Status: REVIEWED

UniProtKB/TrEMBL

X2JCU8

Conserved Domains (1) summary

cd01301
Location:609 → 929

rDP_like; renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. ...
NM_001104120.2 → NP_001097590.1 uncharacterized protein Dmel_CG44837, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001097590.1

Status: REVIEWED

UniProtKB/TrEMBL

Q29R20

Conserved Domains (1) summary

cd01301
Location:446 → 766

rDP_like; renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. ...
NM_140259.2 → NP_648516.2 uncharacterized protein Dmel_CG44837, isoform D [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_648516.2

Status: REVIEWED

UniProtKB/TrEMBL

R9PY29

Conserved Domains (1) summary

cd01301
Location:446 → 766

rDP_like; renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. ...