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    CG13287 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38660, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13287provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035643
    Locus tag
    Dmel_CG13287
    See related
    AllianceGenome:FB:FBgn0035643
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13287
    Summary
    Predicted to enable chromatin binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in central brain primordium; dorsal head epidermis anlage in statu nascendi; embryonic brain; larval ventral nerve cord; and ventral nerve cord primordium. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 10. Orthologous to human PRDM8 (PR/SET domain 8) and ZNF488 (zinc finger protein 488). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13287 in Genome Data Viewer
    Location:
    64F3-64F3; 3-15 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5882304..5884090)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5875404..5877190)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene vein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene DNA polymerase epsilon subunit 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13287-PA
    CG13287-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      5882304..5884090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139737.2 → NP_647994.1  uncharacterized protein Dmel_CG13287, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647994.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W340, Q9VRQ6
      Related
      FBpp0076735
      Conserved Domains (2) summary
      sd00017
      Location:360 → 380
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12756
      Location:363 → 418
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)

    2. NM_001274525.1 → NP_001261454.1  uncharacterized protein Dmel_CG13287, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261454.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F9W340, M9PEQ7
      Conserved Domains (2) summary
      sd00017
      Location:360 → 380
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12756
      Location:363 → 418
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PEQ7 M9PEQ7
    Q9VRQ6 Q9VRQ6

    Gene LinkOut

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