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    CG8915 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32715, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8915provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030833
    Locus tag
    Dmel_CG8915
    See related
    AllianceGenome:FB:FBgn0030833
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg8915; Dmel\CG8915
    Summary
    Predicted to enable 3'-5' RNA helicase activity and RNA binding activity. Is expressed in adult head; germline cell; gonad; organism; and primordial germ cell. Orthologous to human YTHDC2 (YTH N6-methyladenosine RNA binding protein C2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8915 in Genome Data Viewer
    Location:
    15F4-15F4; 1-57 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17240468..17245001, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17134501..17139034, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene forked Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Sanjuán R, et al. Mol Biol Evol, 2001 Mar. PMID 11230534
    2. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article
    3. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
    4. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article
    5. Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. Lowe N, et al. Development, 2014 Oct. PMID 25294943, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 3'-5' RNA helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8915-PA
    CG8915-PB
    helicasa

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17240468..17245001 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298440.1 → NP_001285369.1  uncharacterized protein Dmel_CG8915, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285369.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX63
      Conserved Domains (6) summary
      cd02325
      Location:64 → 123
      R3H; R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich ...
      smart00490
      Location:479 → 575
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:214 → 395
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:648 → 733
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:226 → 368
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:783 → 884
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    2. NM_132980.3 → NP_573208.1  uncharacterized protein Dmel_CG8915, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573208.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX63
      Related
      FBpp0074221
      Conserved Domains (6) summary
      cd02325
      Location:64 → 123
      R3H; R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich ...
      smart00490
      Location:479 → 575
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:214 → 395
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:648 → 733
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:226 → 368
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:783 → 884
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXN5 Q8SXN5
    Q9VX63 Q9VX63

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