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    CG12730 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31466, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12730provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029771
    Locus tag
    Dmel_CG12730
    See related
    AllianceGenome:FB:FBgn0029771
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE01432; Dmel\CG12730
    Summary
    Predicted to be active in membrane. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut; embryonic/larval midgut primordium; and mesoderm. Orthologous to several human genes including CMTM4 (CKLF like MARVEL transmembrane domain containing 4); CMTM6 (CKLF like MARVEL transmembrane domain containing 6); and CMTM8 (CKLF like MARVEL transmembrane domain containing 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12730 in Genome Data Viewer
    Location:
    5A2-5A2; 1-12 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5516608..5518771)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5410641..5412804)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45519 Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45518 Neighboring gene ncRNA Neighboring gene Visual system homeobox 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved role of the Vsx genes supports a monophyletic origin for bilaterian visual systems. Erclik T, et al. Curr Biol, 2008 Sep 9. PMID 18723351
    2. Identification of genes expressed during Drosophila melanogaster gastrulation by using subtractive hybridization. González-Agüero M, et al. Gene, 2005 Jan 31. PMID 15716118
    3. Drosophila glia: Few cell types and many conserved functions. Yildirim K, et al. Glia, 2019 Jan. PMID 30443934
    4. Genome-wide measurement of spatial expression in patterning mutants of Drosophila melanogaster. Combs PA, et al. F1000Res, 2017. PMID 28299188, Free PMC Article
    5. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12730-PA
    CG12730-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5516608..5518771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297967.1 → NP_001284896.1  uncharacterized protein Dmel_CG12730, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4B6

    2. NM_132000.3 → NP_572228.1  uncharacterized protein Dmel_CG12730, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572228.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4B6
      Related
      FBpp0070746
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W4B6 Q9W4B6

    Gene LinkOut

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