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    CG17230 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41376, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17230provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0046225
    Locus tag
    Dmel_CG17230
    See related
    AllianceGenome:FB:FBgn0046225
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH24095; CG5286; Dmel\CG17230
    Summary
    Predicted to be involved in apoptotic process. Predicted to be active in keratin filament. Is expressed in chordotonal neurons; organism; and spermatogonium. Orthologous to human TCHP (trichoplein keratin filament binding). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17230 in Genome Data Viewer
    Location:
    86E5-86E7; 3-51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11437785..11467372)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7263507..7293094)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Exonuclease 3'-5' domain-containing 2 Neighboring gene uncharacterized protein Neighboring gene sarcomere length short Neighboring gene mir-4945 stem loop Neighboring gene Peptidoglycan recognition protein LB Neighboring gene long non-coding RNA:CR45581 Neighboring gene defective proboscis extension response 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Parkhitko AA, et al. Genes Dev, 2016 Jun 15. PMID 27313316, Free PMC Article
    2. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    3. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Ringrose L, et al. Dev Cell, 2003 Nov. PMID 14602076
    4. Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. Lebo MS, et al. BMC Genomics, 2009 Feb 13. PMID 19216785, Free PMC Article
    5. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in keratin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17230-PA
    CG17230-PB
    CG17230-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11437785..11467372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141820.2 → NP_650077.1  uncharacterized protein Dmel_CG17230, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650077.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4X4
      Related
      FBpp0081868
      Conserved Domains (1) summary
      COG1196
      Location:49 → 350
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. NM_001300360.1 → NP_001287289.1  uncharacterized protein Dmel_CG17230, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287289.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4X4
      Conserved Domains (1) summary
      COG1196
      Location:49 → 350
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    3. NM_169394.2 → NP_731578.1  uncharacterized protein Dmel_CG17230, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731578.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4X4
      Related
      FBpp0081869
      Conserved Domains (1) summary
      COG1196
      Location:49 → 350
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K4X4 Q7K4X4

    Gene LinkOut

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