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    CG7514 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38571, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7514provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035567
    Locus tag
    Dmel_CG7514
    See related
    AllianceGenome:FB:FBgn0035567
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7514
    Summary
    Predicted to enable C4-dicarboxylate transmembrane transporter activity; antiporter activity; and sulfur compound transmembrane transporter activity. Predicted to be involved in C4-dicarboxylate transport; inorganic anion transmembrane transport; and thiosulfate transport. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SLC25A11 (solute carrier family 25 member 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7514 in Genome Data Viewer
    Location:
    64B13-64B13; 3-12 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4687587..4688774, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4687587..4688774, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene axotactin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Rho guanine nucleotide exchange factor at 64C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits. Kanellopoulos AK, et al. Cell, 2020 Mar 19. PMID 32200800
    2. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Genetics of alcohol consumption in Drosophila melanogaster. Fochler S, et al. Genes Brain Behav, 2017 Sep. PMID 28627812, Free PMC Article
    5. Chromosomal instability causes sensitivity to metabolic stress. Shaukat Z, et al. Oncogene, 2015 Jul 30. PMID 25347746

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7514-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4687587..4688774 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139666.2 → NP_647923.1  uncharacterized protein Dmel_CG7514 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647923.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZ94
      Related
      FBpp0073223
      Conserved Domains (2) summary
      PTZ00169
      Location:16 → 287
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:19 → 90
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZ94 Q9VZ94

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