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    CG8289 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32741, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8289provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030854
    Locus tag
    Dmel_CG8289
    See related
    AllianceGenome:FB:FBgn0030854
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CC4; Dmel\CG8289
    Summary
    Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in heterochromatin formation. Predicted to be located in pericentric heterochromatin. Is expressed in several structures, including antennal anlage; anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8289 in Genome Data Viewer
    Location:
    16B10-16B10; 1-57 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17633691..17636044, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17527724..17530077, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene corolla Neighboring gene NADH dehydrogenase (ubiquinone) 24 kDa subunit Neighboring gene uncharacterized protein Neighboring gene Rho GTPase activating protein p190

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins. Ameres SL, et al. RNA, 2011 Jan. PMID 21106652, Free PMC Article
    2. Identification of genes involved in the same pathways using a Hidden Markov Model-based approach. Senf A, et al. Bioinformatics, 2009 Nov 15. PMID 19720676
    3. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Okamura K, et al. Nature, 2008 Jun 5. PMID 18463630, Free PMC Article
    4. Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling. Ermanoska B, et al. Nat Commun, 2023 Mar 8. PMID 36890170, Free PMC Article
    5. An endogenous small interfering RNA pathway in Drosophila. Czech B, et al. Nature, 2008 Jun 5. PMID 18463631, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in pericentric heterochromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8289-PA
    CG8289-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17633691..17636044 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298450.1 → NP_001285379.1  uncharacterized protein Dmel_CG8289, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285379.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JFW6
      Conserved Domains (1) summary
      smart00298
      Location:232 → 283
      CHROMO; Chromatin organization modifier domain

    2. NM_133001.3 → NP_573229.1  uncharacterized protein Dmel_CG8289, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573229.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX35
      Related
      FBpp0074258
      Conserved Domains (1) summary
      smart00298
      Location:233 → 284
      CHROMO; Chromatin organization modifier domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VX35 Q9VX35
    X2JFW6 X2JFW6

    Gene LinkOut

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