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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012164.1 RefSeqGene
- Range
-
4953..77063
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_013391.3 → NP_037523.2 dimethylglycine dehydrogenase, mitochondrial precursor
See identical proteins and their annotated locations for NP_037523.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the supported protein.
- Source sequence(s)
-
AA676742, AC008502, AF111858, AK057641, BP276968, CA397896
- Consensus CDS
-
CCDS4044.1
- UniProtKB/Swiss-Prot
- B2RBN0, B4E1J9, Q9UI17
- UniProtKB/TrEMBL
-
B3KQ84
- Related
- ENSP00000255189.3, ENST00000255189.8
- Conserved Domains (6) summary
-
- COG0404
Location:464 → 857
- GcvT; Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]
- COG0665
Location:47 → 435
- DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
- pfam01571
Location:482 → 745
- GCV_T; Aminomethyltransferase folate-binding domain
- pfam08669
Location:753 → 845
- GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
- pfam16350
Location:417 → 472
- FAO_M; FAD dependent oxidoreductase central domain
- cl21454
Location:44 → 90
- NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
RNA
-
NR_104002.3 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks three internal exons and contains an alternate 3' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC008502, AC020937, AF111858, AI302996, AK300894, BC022388, BP276968, BP425307
- Related
-
ENST00000523732.1
-
NR_104003.3 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks five internal exons and contains an alternate 3' terminal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC008502, AC020937, AI302996, AK303873, BC022388, BP276968, BP425307
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p14 Primary Assembly
- Range
-
78997564..79069674 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011543355.3 → XP_011541657.1 dimethylglycine dehydrogenase, mitochondrial isoform X2
- UniProtKB/TrEMBL
-
B3KQ84
- Conserved Domains (5) summary
-
- COG0404
Location:464 → 750
- GcvT; Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]
- COG0665
Location:47 → 435
- DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
- pfam01571
Location:482 → 745
- GCV_T; Aminomethyltransferase folate-binding domain
- pfam16350
Location:417 → 472
- FAO_M; FAD dependent oxidoreductase central domain
- cl21454
Location:44 → 90
- NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
-
XM_006714597.3 → XP_006714660.1 dimethylglycine dehydrogenase, mitochondrial isoform X1
- UniProtKB/TrEMBL
-
B3KQ84
- Conserved Domains (5) summary
-
- COG0404
Location:464 → 751
- GcvT; Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]
- COG0665
Location:47 → 435
- DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
- pfam01571
Location:482 → 745
- GCV_T; Aminomethyltransferase folate-binding domain
- pfam16350
Location:417 → 472
- FAO_M; FAD dependent oxidoreductase central domain
- cl21454
Location:44 → 90
- NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Alternate T2T-CHM13v2.0
Genomic
-
NC_060929.1 Alternate T2T-CHM13v2.0
- Range
-
79478676..79550778 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054352476.1 → XP_054208451.1 dimethylglycine dehydrogenase, mitochondrial isoform X2
- UniProtKB/TrEMBL
-
B3KQ84
-
XM_054352475.1 → XP_054208450.1 dimethylglycine dehydrogenase, mitochondrial isoform X1
- UniProtKB/TrEMBL
-
B3KQ84