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    Gnl1 G protein nucleolar 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309593, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gnl1provided by RGD
    Official Full Name
    G protein nucleolar 1provided by RGD
    Primary source
    RGD:1303051
    See related
    EnsemblRapid:ENSRNOG00000000798 AllianceGenome:RGD:1303051
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in DNA damage response. Orthologous to human GNL1 (G protein nucleolar 1 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 152.5), Kidney (RPKM 114.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gnl1 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (2787939..2796924, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (2783130..2792115, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3290543..3299494, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483848 Neighboring gene RT1 class I, locus T24, gene 1 Neighboring gene uncharacterized LOC134483845 Neighboring gene proline rich 3 Neighboring gene ATP binding cassette subfamily F member 1 Neighboring gene microRNA 877

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Matsuoka S, et al. Science, 2007 May 25. PMID 17525332
    2. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA damage response ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212500.3 → NP_997665.1  guanine nucleotide-binding protein-like 1

      See identical proteins and their annotated locations for NP_997665.1

      Status: VALIDATED

      Source sequence(s)
      BC129081, BX883048
      UniProtKB/Swiss-Prot
      Q6MG06
      UniProtKB/TrEMBL
      A0A0G2K6Q5, A6KT59
      Related
      ENSRNOP00000098187.1, ENSRNOT00000120545.2
      Conserved Domains (2) summary
      cd01857
      Location:177 → 418
      HSR1_MMR1; A circularly permuted subfamily of the Ras GTPases
      PRK09563
      Location:179 → 516
      rbgA; GTPase YlqF; Reviewed

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      2787939..2796924 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6MG06.1 GenPept UniProtKB/Swiss-Prot:Q6MG06

    Gene LinkOut

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