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    Btbd9 BTB domain containing 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294318, updated on 9-Dec-2024

    Summary

    Official Symbol
    Btbd9provided by RGD
    Official Full Name
    BTB domain containing 9provided by RGD
    Primary source
    RGD:1306975
    See related
    EnsemblRapid:ENSRNOG00000000540 AllianceGenome:RGD:1306975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in adult locomotory behavior; circadian behavior; and modulation of chemical synaptic transmission. Predicted to act upstream of or within several processes, including circadian sleep/wake cycle, non-REM sleep; long-term memory; and multicellular organismal-level iron ion homeostasis. Predicted to be active in cytoplasm and glutamatergic synapse. Orthologous to human BTBD9 (BTB domain containing 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 61.9), Thymus (RPKM 57.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Btbd9 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (8287813..8645437, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (8286337..8645567, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (8899286..9253936, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098952 Neighboring gene zinc finger AN1-type containing 3 Neighboring gene uncharacterized LOC134483873 Neighboring gene uncharacterized LOC120098951 Neighboring gene keratin-associated protein 5-1-like Neighboring gene uncharacterized LOC102548069 Neighboring gene glyoxalase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm  
    is_active_in glutamatergic synapse  

    General protein information

    Preferred Names
    BTB/POZ domain-containing protein 9
    Names
    BTB (POZ) domain containing 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013073.2NP_001013091.1  BTB/POZ domain-containing protein 9 isoform 1

      See identical proteins and their annotated locations for NP_001013091.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/Swiss-Prot
      Q5PQR3
      Related
      ENSRNOP00000000649.6, ENSRNOT00000000649.8
      Conserved Domains (4) summary
      smart00225
      Location:37137
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd14822
      Location:137196
      BACK_BTBD9_like; BACK-like Domain C-terminal to BTB in BTB/POZ domain-containing protein 9 and similar proteins
      pfam00651
      Location:33134
      BTB; BTB/POZ domain
      pfam00754
      Location:292405
      F5_F8_type_C; F5/8 type C domain
    2. NM_001434573.1NP_001421502.1  BTB/POZ domain-containing protein 9 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/Swiss-Prot
      Q5PQR3
    3. NM_001434574.1NP_001421503.1  BTB/POZ domain-containing protein 9 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
    4. NM_001434576.1NP_001421505.1  BTB/POZ domain-containing protein 9 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      8287813..8645437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006256185.5XP_006256247.1  BTB/POZ domain-containing protein 9 isoform X3

      Conserved Domains (4) summary
      smart00225
      Location:37137
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd14822
      Location:137196
      BACK_BTBD9_like; BACK-like Domain C-terminal to BTB in BTB/POZ domain-containing protein 9 and similar proteins
      pfam00651
      Location:33134
      BTB; BTB/POZ domain
      pfam00754
      Location:292405
      F5_F8_type_C; F5/8 type C domain
    2. XM_063279037.1XP_063135107.1  BTB/POZ domain-containing protein 9 isoform X1

    3. XM_063279038.1XP_063135108.1  BTB/POZ domain-containing protein 9 isoform X2

    4. XM_063279040.1XP_063135110.1  BTB/POZ domain-containing protein 9 isoform X6

    5. XM_039098534.2XP_038954462.1  BTB/POZ domain-containing protein 9 isoform X8

      Conserved Domains (2) summary
      cd18287
      Location:14133
      BTB_POZ_BTBD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
      cd14822
      Location:137235
      BACK_BTBD9; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
    6. XM_063279039.1XP_063135109.1  BTB/POZ domain-containing protein 9 isoform X5

    7. XM_039098533.2XP_038954461.1  BTB/POZ domain-containing protein 9 isoform X4

      Conserved Domains (2) summary
      cd18287
      Location:14133
      BTB_POZ_BTBD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
      cd14822
      Location:137235
      BACK_BTBD9; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
    8. XM_039098536.1XP_038954464.1  BTB/POZ domain-containing protein 9 isoform X7

      Conserved Domains (2) summary
      cd18287
      Location:14133
      BTB_POZ_BTBD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 9 (BTBD9)
      cd14822
      Location:137235
      BACK_BTBD9; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 9 (BTBD9)

    RNA

    1. XR_010060644.1 RNA Sequence

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