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    CDK8 cyclin dependent kinase 8 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 102131185, updated on 12-Jun-2024

    Summary

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    Gene symbol
    CDK8
    Gene description
    cyclin dependent kinase 8
    See related
    Ensembl:ENSMFAG00000003010
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CDK8 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 17 NC_088391.1 (6306812..6457595)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 17 NC_052271.1 (5663096..5813670)

    Chromosome 17 - NC_088391.1Genomic Context describing neighboring genes Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase-like Neighboring gene ring finger protein 6 Neighboring gene neuronal regeneration-related protein-like Neighboring gene uncharacterized LOC135968070 Neighboring gene uncharacterized LOC135967985 Neighboring gene small ribosomal subunit protein eS1-like Neighboring gene WASP family member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assignment of 118 novel cDNAs of cynomolgus monkey brain to human chromosomes. Osada N, et al. Gene, 2001 Sep 5. PMID 11574149
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 8
    Names
    Cell division protein kinase 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088391.1 Reference T2T-MFA8v1.0

      Range
      6306812..6457595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005585519.4 → XP_005585576.1  cyclin-dependent kinase 8 isoform X1

      See identical proteins and their annotated locations for XP_005585576.1

      UniProtKB/TrEMBL
      A0A2K5W7E0
      Related
      ENSMFAP00000032978.1
      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    2. XM_005585520.4 → XP_005585577.1  cyclin-dependent kinase 8 isoform X2

      See identical proteins and their annotated locations for XP_005585577.1

      UniProtKB/TrEMBL
      G7PVW1
      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    3. XM_065533083.1 → XP_065389155.1  cyclin-dependent kinase 8 isoform X3

    Nucleotide Protein
    Heading Accession and Version

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