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    Rtp3 receptor (chemosensory) transporter protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316018, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rtp3provided by RGD
    Official Full Name
    receptor (chemosensory) transporter protein 3provided by RGD
    Primary source
    RGD:1310546
    See related
    EnsemblRapid:ENSRNOG00000037167 AllianceGenome:RGD:1310546
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem7
    Summary
    Predicted to enable olfactory receptor binding activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste; protein insertion into membrane; and protein targeting to membrane. Predicted to be active in cytoplasm. Orthologous to human RTP3 (receptor transporter protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 82.2), Spleen (RPKM 7.3) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rtp3 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (119847947..119853549, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (110970154..110975000, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (119260609..119265501, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene cripto, EGF-CFC family member Neighboring gene leucine rich repeat containing 2 Neighboring gene elongin B like 7 Neighboring gene lactotransferrin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Members of RTP and REEP gene families influence functional bitter taste receptor expression. Behrens M, et al. J Biol Chem, 2006 Jul 21. PMID 16720576
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables olfactory receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein insertion into membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein targeting to membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    receptor-transporting protein 3
    Names
    receptor transporter protein 3
    transmembrane protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108190.2 → NP_001101660.1  receptor-transporting protein 3

      See identical proteins and their annotated locations for NP_001101660.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I3I4, D4A1N0
      Related
      ENSRNOP00000052950.2, ENSRNOT00000056100.4
      Conserved Domains (2) summary
      PHA03247
      Location:172 → 375
      PHA03247; large tegument protein UL36; Provisional
      pfam13695
      Location:49 → 161
      zf-3CxxC; Zinc-binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      119847947..119853549 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006243965.5 → XP_006244027.1  receptor-transporting protein 3 isoform X1

      Conserved Domains (2) summary
      PHA03247
      Location:172 → 375
      PHA03247; large tegument protein UL36; Provisional
      pfam13695
      Location:49 → 161
      zf-3CxxC; Zinc-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

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