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    Zfp710 zinc finger protein 710 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293044, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp710provided by RGD
    Official Full Name
    zinc finger protein 710provided by RGD
    Primary source
    RGD:1306491
    See related
    EnsemblRapid:ENSRNOG00000014278 AllianceGenome:RGD:1306491
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf710; RGD1306491
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF710 (zinc finger protein 710). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 49.1), Spleen (RPKM 47.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp710 in Genome Data Viewer
    Location:
    1q31
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (143375524..143445874)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (133966256..134036593)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (141763621..141873371)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483742 Neighboring gene uncharacterized LOC120099870 Neighboring gene actin-related protein 2/3 complex inhibitor Neighboring gene uncharacterized LOC134483743 Neighboring gene isocitrate dehydrogenase (NADP(+)) 2 Neighboring gene N(alpha)-acetyltransferase 38, NatC auxiliary subunit, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 710

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398728.1 → NP_001385657.1  zinc finger protein 710

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6JC77
      Related
      ENSRNOP00000082047.2, ENSRNOT00000118154.2
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      143375524..143445874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008759507.4 → XP_008757729.2  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Related
      ENSRNOP00000061568.4, ENSRNOT00000064034.4
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    2. XM_063284601.1 → XP_063140671.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77

    3. XM_039105619.2 → XP_038961547.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    4. XM_039105622.2 → XP_038961550.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    5. XM_039105628.2 → XP_038961556.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    6. XM_039105620.2 → XP_038961548.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    7. XM_039105625.2 → XP_038961553.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    8. XM_039105626.2 → XP_038961554.1  zinc finger protein 710 isoform X1

      UniProtKB/TrEMBL
      A6JC77
      Conserved Domains (4) summary
      COG5048
      Location:417 → 594
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:348 → 402
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:298 → 318
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:338 → 363
      zf-H2C2_2; Zinc-finger double domain

    9. XM_063284615.1 → XP_063140685.1  zinc finger protein 710 isoform X2

      UniProtKB/TrEMBL
      D4A0K8
      Related
      ENSRNOP00000102310.1, ENSRNOT00000133165.1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001134563.1: Suppressed sequence

      Description
      NM_001134563.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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