Myg1 MYG1 exonuclease [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Myg1provided by RGD
Official Full Name: MYG1 exonucleaseprovided by RGD
Primary source: RGD:1359237
See related: EnsemblRapid:ENSRNOG00000013343 AllianceGenome:RGD:1359237
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: C12orf10
Summary: Predicted to enable nuclease activity. Predicted to act upstream of or within locomotory exploration behavior. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human MYG1 (MYG1 exonuclease). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 149.3), Kidney (RPKM 126.9) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q36

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (135335364..135342567)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (133456778..133463985)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (143929662..143936865)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH131256 (e-PCR)
- UniSTS:214539

RH127371 (e-PCR)
- UniSTS:210681

RH140854 (e-PCR)
- UniSTS:210681

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 3'-5'-RNA exonuclease activity	IEA Inferred from Electronic Annotation more info
enables 3'-5'-RNA exonuclease activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within locomotory exploration behavior	ISO Inferred from Sequence Orthology more info
involved_in mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA processing	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial RNA metabolic process	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial RNA metabolic process	ISO Inferred from Sequence Orthology more info
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in rRNA processing	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial matrix	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
is_active_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: MYG1 exonuclease

Names: UPF0160 protein MYG1, mitochondrial; melanocyte proliferating gene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005545.1 → NP_001005545.1 MYG1 exonuclease precursor

See identical proteins and their annotated locations for NP_001005545.1

Status: PROVISIONAL

Source sequence(s)

BC082112

UniProtKB/Swiss-Prot

Q641W2

Related

ENSRNOP00000017942.3, ENSRNOT00000017942.8

Conserved Domains (1) summary

pfam03690
Location:46 → 366

UPF0160; uncharacterized protein family (UPF0160)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086025.1 Reference GRCr8

Range

135335364..135342567

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039078940.2 → XP_038934868.1 MYG1 exonuclease isoform X1

Conserved Domains (1) summary

pfam03690
Location:2 → 257

UPF0160; Uncharacterized protein family (UPF0160)