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    Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294881, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc7a12provided by RGD
    Official Full Name
    solute carrier family 7 (cationic amino acid transporter, y+ system), member 12provided by RGD
    Primary source
    RGD:1309208
    See related
    EnsemblRapid:ENSRNOG00000033830 AllianceGenome:RGD:1309208
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within amino acid transport. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 843.1) See more
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    Genomic context

    See Slc7a12 in Genome Data Viewer
    Location:
    2q23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (88800954..88868117, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (87079724..87146875, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (88559677..88660449, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) Neighboring gene E2F transcription factor 5 Neighboring gene leucine rich repeat and coiled-coil centrosomal protein 1 Neighboring gene solute carrier family 7 member 13, pseudogene 1 Neighboring gene leucine-rich repeat and coiled-coil domain-containing protein 1-like Neighboring gene uncharacterized LOC134485875

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC94806

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables amino acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within amino acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 7 (cationic amino acid transporter, y+ system), member 12

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011948.1NP_001011948.1  solute carrier family 7 (cationic amino acid transporter, y+ system), member 12

      See identical proteins and their annotated locations for NP_001011948.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078940
      UniProtKB/TrEMBL
      Q6AYR7
      Related
      ENSRNOP00000050128.2, ENSRNOT00000051741.6
      Conserved Domains (1) summary
      TIGR00911
      Location:21423
      2A0308; L-type amino acid transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      88800954..88868117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281531.1XP_063137601.1  solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 isoform X1