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    Cyssl1 cystatin S like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296235, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cyssl1provided by RGD
    Official Full Name
    cystatin S like 1provided by RGD
    Primary source
    RGD:1565109
    See related
    EnsemblRapid:ENSRNOG00000036952 AllianceGenome:RGD:1565109
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be active in cytoplasm; extracellular space; and vesicle. Orthologous to human CST4 (cystatin S) and CST1 (cystatin SN). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Cyssl1 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (157944699..157949905, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (137484098..137489304, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (144480098..144485304, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene cystatin S Neighboring gene cystatin S like 3 Neighboring gene cystatin D Neighboring gene uncharacterized LOC134486463 Neighboring gene uncharacterized LOC102551848

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC124773

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cystatin S like 1
    Names
    cystatin S-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037350.1NP_001032427.1  cystatin S like 1 precursor

      See identical proteins and their annotated locations for NP_001032427.1

      Status: PROVISIONAL

      Source sequence(s)
      BC101872
      UniProtKB/TrEMBL
      A6K7F5, G3V9M0, Q3MIE8
      Related
      ENSRNOP00000052385.2, ENSRNOT00000055522.6
      Conserved Domains (1) summary
      smart00043
      Location:29141
      CY; Cystatin-like domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      157944699..157949905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)