U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Trpc4ap transient receptor potential cation channel, subfamily C, member 4 associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362247, updated on 27-Nov-2024

    Summary

    Official Symbol
    Trpc4approvided by RGD
    Official Full Name
    transient receptor potential cation channel, subfamily C, member 4 associated proteinprovided by RGD
    Primary source
    RGD:1309914
    See related
    EnsemblRapid:ENSRNOG00000019152 AllianceGenome:RGD:1309914
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable phosphatase binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Predicted to act upstream of or within hair follicle maturation. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex. Orthologous to human TRPC4AP (transient receptor potential cation channel subfamily C member 4 associated protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 357.3), Muscle (RPKM 329.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Trpc4ap in Genome Data Viewer
    Location:
    3q42
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (164582146..164653123, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (144122003..144192986, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (151150396..151224123, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene glutathione synthetase Neighboring gene myosin heavy chain 7B Neighboring gene microRNA 499a Neighboring gene ER degradation enhancing alpha-mannosidase like protein 2 Neighboring gene protein C receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General protein information

    Preferred Names
    short transient receptor potential channel 4-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100748.1NP_001094218.1  short transient receptor potential channel 4-associated protein

      See identical proteins and their annotated locations for NP_001094218.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474050
      UniProtKB/TrEMBL
      A6KI51, A6KI52, B2RYF4, F7FBB0, Q5M940
      Related
      ENSRNOP00000026091.4, ENSRNOT00000026091.6
      Conserved Domains (1) summary
      pfam12463
      Location:407713
      DUF3689; Protein of unknown function (DUF3689)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      164582146..164653123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)