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    Chst14 carbohydrate sulfotransferase 14 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691394, updated on 27-Nov-2024

    Summary

    Official Symbol
    Chst14provided by RGD
    Official Full Name
    carbohydrate sulfotransferase 14provided by RGD
    Primary source
    RGD:1585023
    See related
    AllianceGenome:RGD:1585023
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate proteoglycan metabolic process. Predicted to act upstream of or within dermatan sulfate biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See Chst14 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (126370348..126372405)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (105916481..105918538)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (110734105..110736162)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486300 Neighboring gene bromo adjacent homology domain containing 1 Neighboring gene uncharacterized LOC134486301 Neighboring gene coiled-coil domain containing 32

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables dermatan 4-sulfotransferase ISO
    Inferred from Sequence Orthology
    more info
     
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in carbohydrate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within dermatan sulfate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dermatan sulfate proteoglycan metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dermatan sulfate proteoglycan metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carbohydrate sulfotransferase 14
    Names
    carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
    dermatan 4 sulfotransferase 1
    NP_001103109.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109639.1NP_001103109.1  carbohydrate sulfotransferase 14

      See identical proteins and their annotated locations for NP_001103109.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473949
      UniProtKB/TrEMBL
      B2GV63, M0R8Y4
      Conserved Domains (1) summary
      pfam03567
      Location:144364
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      126370348..126372405
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)