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    Tmem266 transmembrane protein 266 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501002, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem266provided by RGD
    Official Full Name
    transmembrane protein 266provided by RGD
    Primary source
    RGD:1562084
    See related
    EnsemblRapid:ENSRNOG00000015201 AllianceGenome:RGD:1562084
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562084
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in metal ion transport and monoatomic cation transmembrane transport. Predicted to be located in cytosol. Predicted to be active in dendrite and plasma membrane. Orthologous to human TMEM266 (transmembrane protein 266). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 33.6), Kidney (RPKM 5.6) and 2 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmem266 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (64603199..64716770)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (55707122..55820692)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (59952732..60014363)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene Serpine1 mRNA binding protein 1, pseudogene 1 Neighboring gene F-box/LRR-repeat protein 14-like Neighboring gene uncharacterized LOC134480178 Neighboring gene electron transfer flavoprotein subunit alpha Neighboring gene bolA family member 2, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    NOT enables voltage-gated channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 266
    Names
    transmembrane protein C15orf27 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109294.1NP_001102764.1  transmembrane protein 266

      See identical proteins and their annotated locations for NP_001102764.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473975
      UniProtKB/TrEMBL
      A0A8I6AI08, A6J4P5, D3ZYW8
      Related
      ENSRNOP00000020410.4, ENSRNOT00000020410.7
      Conserved Domains (1) summary
      pfam00520
      Location:118210
      Ion_trans; Ion transport protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      64603199..64716770
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081961.2XP_038937889.1  transmembrane protein 266 isoform X1

    2. XM_063265988.1XP_063122058.1  transmembrane protein 266 isoform X2