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    Cox6c cytochrome c oxidase subunit 6C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 54322, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cox6cprovided by RGD
    Official Full Name
    cytochrome c oxidase subunit 6Cprovided by RGD
    Primary source
    RGD:620616
    See related
    EnsemblRapid:ENSRNOG00000010807 AllianceGenome:RGD:620616
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    COVIc; Cox6c2; COX-VIc
    Summary
    Predicted to be involved in oxidative phosphorylation and proton transmembrane transport. Predicted to be located in mitochondrial membrane. Orthologous to human COX6C (cytochrome c oxidase subunit 6C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 7940.8), Muscle (RPKM 5387.3) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cox6c in Genome Data Viewer
    Location:
    7q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (69014410..69027145, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (67129265..67142001, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (74723177..74735650, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 13 homolog B Neighboring gene ATM interactor, pseudogene 2 Neighboring gene microRNA 875 Neighboring gene pre-mRNA-splicing factor CWC22 homolog Neighboring gene ribosomal protein S24, pseudogene 17

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    cytochrome c oxidase subunit 6C-2
    Names
    cytochrome c oxidase polypeptide VIc-2
    cytochrome c oxidase, subunit VIc
    cytochrome oxidase subunit VIc

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019360.2NP_062233.2  cytochrome c oxidase subunit 6C-2

      See identical proteins and their annotated locations for NP_062233.2

      Status: VALIDATED

      Source sequence(s)
      AI716762, BC058480, CF976717
      UniProtKB/Swiss-Prot
      P11951, Q63703
      UniProtKB/TrEMBL
      A6HR20
      Related
      ENSRNOP00000014407.2, ENSRNOT00000014407.7
      Conserved Domains (1) summary
      pfam02937
      Location:675
      COX6C; Cytochrome c oxidase subunit VIc

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      69014410..69027145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)