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    Ccdc166 coiled-coil domain containing 166 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680799, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc166provided by RGD
    Official Full Name
    coiled-coil domain containing 166provided by RGD
    Primary source
    RGD:1588167
    See related
    EnsemblRapid:ENSRNOG00000047521 AllianceGenome:RGD:1588167
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human CCDC166 (coiled-coil domain containing 166). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 37.8) and Brain (RPKM 4.2) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc166 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109574271..109576074, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107693572..107695375, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117039890..117041693, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093815 Neighboring gene zinc finger protein 707-like 1 Neighboring gene zinc finger protein 707 Neighboring gene mitogen-activated protein kinase 15 Neighboring gene family with sequence similarity 83, member H Neighboring gene IQ motif and ankyrin repeat containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 166

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130509.2 → NP_001123981.2  coiled-coil domain-containing protein 166 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
      Source sequence(s)
      BC160829
      UniProtKB/TrEMBL
      M0R4R5
      Related
      ENSRNOP00000064360.2, ENSRNOT00000073835.4
      Conserved Domains (3) summary
      pfam03035
      Location:309 → 394
      RNA_capsid; Calicivirus putative RNA polymerase/capsid protein
      pfam14988
      Location:69 → 255
      DUF4515; Domain of unknown function (DUF4515)
      cl19252
      Location:206 → 254
      MreC; rod shape-determining protein MreC

    2. NM_001163519.1 → NP_001156991.1  coiled-coil domain-containing protein 166 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) retains an intron resulting in a frameshift, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      BC160829
      Conserved Domains (1) summary
      pfam14988
      Location:69 → 145
      DUF4515; Domain of unknown function (DUF4515)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      109574271..109576074 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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