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    xdhA putative xanthine dehydrogenase molybdenum-binding subunit XdhA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947116, updated on 3-Dec-2024

    Summary

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    Official Symbol
    xdhA
    Official Full Name
    putative xanthine dehydrogenase molybdenum-binding subunit XdhA
    Primary source
    ECOCYC:G7485
    Locus tag
    b2866
    See related
    ASAP:ABE-0009413
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2862; ygeS
    Summary
    AFMB Structural Genomics target Number 102 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG13049]. XdhA has similarity to the molybdenum cofactor-containing domains of Drosophila melanogaster xanthine dehydrogenase and Desulfovibrio gigas aldehyde oxidoreductase . [More information is available at EcoCyc: G7485].
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    Genomic context

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    Sequence:
    NC_000913.3 (3000345..3002603)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene amidase activator Neighboring gene putative xanthine dehydrogenase FAD-binding subunit XdhB Neighboring gene putative xanthine dehydrogenase iron-sulfur-binding subunit XdhC Neighboring gene putative sigma(54)-dependent transcriptional regulator YgeV

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molybdenum enzymes, their maturation and molybdenum cofactor biosynthesis in Escherichia coli. Iobbi-Nivol C, et al. Biochim Biophys Acta, 2013 Aug-Sep. PMID 23201473
    2. Molybdenum cofactor-dependent resistance to N-hydroxylated base analogs in Escherichia coli is independent of MobA function. Kozmin SG, et al. Mutat Res, 2007 Jun 1. PMID 17349664, Free PMC Article
    3. Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage. Xi H, et al. J Bacteriol, 2000 Oct. PMID 10986234, Free PMC Article
    4. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables xanthine dehydrogenase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables xanthine dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in hypoxanthine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in hypoxanthine catabolic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in purine nucleobase metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in purine ribonucleoside salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in purine ribonucleoside salvage NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of xanthine dehydrogenase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of xanthine dehydrogenase complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative xanthine dehydrogenase molybdenum-binding subunit XdhA
    NP_417342.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3000345..3002603
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417342.1 putative xanthine dehydrogenase molybdenum-binding subunit XdhA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417342.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      B7MM53, C3SW79, C3SW80
      Conserved Domains (1) summary
      PRK09970
      Location:1 → 752
      PRK09970; xanthine dehydrogenase subunit XdhA; Provisional
    Nucleotide Protein
    Heading Accession and Version

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