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    recJ ssDNA-specific exonuclease RecJ [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947367, updated on 17-Dec-2024

    Summary

    Official Symbol
    recJ
    Official Full Name
    ssDNA-specific exonuclease RecJ
    Primary source
    ECOCYC:EG10830
    Locus tag
    b2892
    See related
    ASAP:ABE-0009492
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2887
    Summary
    Lovett and Kolodner (1989) N-terminally sequenced RecJ, but the native RBS was not used to direct translation, so it has been removed from the Verified Set. [More information is available at EcoGene: EG10830]. Three essential activities for the initiation of recombination in the recB1080 mutant are provided by different proteins: helicase activity by RecB1080CD, 5' --> 3' exonuclease by RecJ, and RecA-single-stranded DNA filament formation by RecFOR. [More information is available at EcoCyc: EG10830].
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    Genomic context

    Sequence:
    NC_000913.3 (3036373..3038106, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene lysine--tRNA ligase Neighboring gene peptide chain release factor RF2 Neighboring gene protein disulfide isomerase DsbC Neighboring gene site-specific recombinase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 5'-3' exonuclease activity  
    enables exonuclease activity  
    enables nucleic acid binding  
    enables protein binding PubMed 
    enables single-stranded DNA 5'-3' DNA exonuclease activity  
    enables single-stranded DNA 5'-3' DNA exonuclease activity PubMed 
    Process Evidence Code Pubs
    involved_in DNA recombination  
    involved_in DNA recombination  
    acts_upstream_of_or_within DNA recombination PubMed 
    involved_in DNA repair  
    acts_upstream_of_or_within DNA repair PubMed 
    acts_upstream_of_or_within response to X-ray PubMed 

    General protein information

    Preferred Names
    ssDNA-specific exonuclease RecJ
    NP_417368.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3036373..3038106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417368.1 ssDNA-specific exonuclease RecJ [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417368.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7L7EH15, A0A8S7EIK8
      Conserved Domains (1) summary
      PRK11070
      Location:3577
      PRK11070; single-stranded-DNA-specific exonuclease RecJ
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