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    nuoC NADH:quinone oxidoreductase subunit CD [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946759, updated on 3-Dec-2024

    Summary

    Official Symbol
    nuoC
    Official Full Name
    NADH:quinone oxidoreductase subunit CD
    Primary source
    ECOCYC:EG12084
    Locus tag
    b2286
    See related
    ASAP:ABE-0007549
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2280; nuoD
    Summary
    Leif (1995) find the starting amino acids at codon +4 (MVNN), in conflict with the more recent data of David (2002), which does not include these 4 amino acids and the initial Met. [More information is available at EcoGene: EG12084]. NuoC is part of the connecting fragment of NADH dehydrogenase I . [More information is available at EcoCyc: EG12084].
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    Genomic context

    Sequence:
    NC_000913.3 (2402055..2403845, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene NADH:quinone oxidoreductase subunit H Neighboring gene NADH:quinone oxidoreductase subunit G Neighboring gene NADH:quinone oxidoreductase subunit F Neighboring gene NADH:quinone oxidoreductase subunit E Neighboring gene NADH:quinone oxidoreductase subunit B Neighboring gene NADH:quinone oxidoreductase subunit A

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to NADH dehydrogenase (ubiquinone) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables NADH dehydrogenase (ubiquinone) activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to NADH dehydrogenase (ubiquinone) activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    contributes_to NADH dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables NADH:ubiquinone reductase (non-electrogenic) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables quinone binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in respiratory electron transport chain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of NADH dehydrogenase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of NADH dehydrogenase complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane HDA PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of respiratory chain complex I IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    part_of respiratory chain complex I NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    NADH:quinone oxidoreductase subunit CD
    NP_416789.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2402055..2403845 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416789.2 NADH:quinone oxidoreductase subunit CD [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416789.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q0TFG0
      UniProtKB/TrEMBL
      A0A0A0FSU8, A0AAN4NSZ5
      Conserved Domains (1) summary
      PRK11742
      Location:21596
      PRK11742; bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional