Zfp616 zinc finger protein 616 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp616provided by MGI
Official Full Name: zinc finger protein 616provided by MGI
Primary source: MGI:MGI:3650906
See related: Ensembl:ENSMUSG00000069476 AllianceGenome:MGI:3650906
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm12330
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cellular response to zinc ion; regulation of DNA-templated transcription; and ribosome biogenesis. Orthologous to human ZNF658 (zinc finger protein 658). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 11 B4; 11 45.74 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (73951723..73978127)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (74060897..74087301)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:489490

NoName (e-PCR)
- UniSTS:489491

NoName (e-PCR)
- UniSTS:494373

NoName (e-PCR)
- UniSTS:495660

NoName (e-PCR)
- UniSTS:495661

NoName (e-PCR)
- UniSTS:485204

NoName (e-PCR)
- UniSTS:485205

NoName (e-PCR)
- UniSTS:489326

NoName (e-PCR)
- UniSTS:494973

Olfr399 (e-PCR), detects polymorphism
- UniSTS:531367

NoName (e-PCR)
- UniSTS:491694

NoName (e-PCR)
- UniSTS:492725

NoName (e-PCR)
- UniSTS:495591

NoName (e-PCR)
- UniSTS:495339

NoName (e-PCR)
- UniSTS:491761

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription cis-regulatory region binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular response to zinc ion	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosome biogenesis	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger protein 616

Names: KRAB box containing protein; novel KRAB box containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177570.1 → NP_001171041.1 zinc finger protein 616

Status: VALIDATED

Source sequence(s)

AL611937

Consensus CDS

CCDS56793.1

UniProtKB/TrEMBL

J3QN14

Related

ENSMUSP00000136549.2, ENSMUST00000178159.2

Conserved Domains (4) summary

COG5048
Location:506 → 914

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:707 → 727

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:705 → 727

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:943 → 968

zf-H2C2_2; Zinc-finger double domain