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    fgfbp1b fibroblast growth factor binding protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 101886353, updated on 4-Jan-2025

    Summary

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    Official Symbol
    fgfbp1bprovided by ZNC
    Official Full Name
    fibroblast growth factor binding protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081106-1
    See related
    Ensembl:ENSDARG00000091660 AllianceGenome:ZFIN:ZDB-GENE-081106-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc20g06
    Summary
    Predicted to enable growth factor binding activity. Predicted to be involved in cell-cell signaling. Predicted to be located in extracellular region. Is expressed in brain; head; and otic vesicle. Orthologous to human FGFBP1 (fibroblast growth factor binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See fgfbp1b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (22676698..22678468, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (21985958..21987829, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) Neighboring gene annexin A5b Neighboring gene fibroblast growth factor binding protein 2b Neighboring gene zinc finger, MYND-type containing 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Temporal and spatial expression of fgfbp genes in zebrafish. Li Y, et al. Gene, 2018 Jun 15. PMID 29551495
    2. A zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans. Krall M, et al. Hum Genet, 2018 Apr. PMID 29713869, Free PMC Article
    3. Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression. Madera D, et al. Int J Mol Sci, 2023 Dec 19. PMID 38203224, Free PMC Article
    4. Genetic control of cellular morphogenesis in Müller glia. Charlton-Perkins M, et al. Glia, 2019 Jul. PMID 30924555, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables growth factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fibroblast growth factor-binding protein 1
    Names
    fgfbp1
    fibroblast growth factor-binding protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      22676698..22678468 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476334.2 → XP_021332009.1  fibroblast growth factor-binding protein 1

      UniProtKB/TrEMBL
      A0A8M9Q0I5, E7FEC7
      Related
      ENSDARP00000105647.1, ENSDART00000128918.3
      Conserved Domains (1) summary
      pfam06473
      Location:10 → 203
      FGF-BP1; FGF binding protein 1 (FGF-BP1)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394480.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      10234..12004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021471190.2 → XP_021326865.1  fibroblast growth factor-binding protein 1

      UniProtKB/TrEMBL
      A0A8M9Q0I5, E7FEC7
      Conserved Domains (1) summary
      pfam06473
      Location:10 → 203
      FGF-BP1; FGF binding protein 1 (FGF-BP1)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395214.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      10234..12004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005170938.5 → XP_005170995.1  fibroblast growth factor-binding protein 1

      UniProtKB/TrEMBL
      A0A8M9Q0I5, E7FEC7
      Conserved Domains (1) summary
      pfam06473
      Location:10 → 203
      FGF-BP1; FGF binding protein 1 (FGF-BP1)
    Nucleotide Protein Strain
    Heading Accession and Version

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