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    ncoa5 nuclear receptor coactivator 5 [ Danio rerio (zebrafish) ]

    Gene ID: 447849, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ncoa5provided by ZNC
    Official Full Name
    nuclear receptor coactivator 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-155
    See related
    Ensembl:ENSDARG00000016345 AllianceGenome:ZFIN:ZDB-GENE-040912-155
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92194
    Summary
    Predicted to enable RNA binding activity. Orthologous to human NCOA5 (nuclear receptor coactivator 5). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See ncoa5 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (55424558..55437091)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (55413124..55425766)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene phospholipid transfer protein Neighboring gene cathepsin A Neighboring gene solute carrier family 12 member 5a Neighboring gene EYA transcriptional coactivator and phosphatase 2 Neighboring gene uncharacterized LOC101882786 Neighboring gene uncharacterized LOC101886558 Neighboring gene N-acetyltransferase 8-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comprehensive Transcriptome Analysis Reveals Sex-Specific Alternative Splicing Events in Zebrafish Gonads. Lin X, et al. Life (Basel), 2022 Sep 16. PMID 36143477, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    nuclear receptor coactivator 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004588.1 → NP_001004588.1  nuclear receptor coactivator 5

      See identical proteins and their annotated locations for NP_001004588.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081621
      UniProtKB/TrEMBL
      A0A8M1N283, Q66HY6
      Related
      ENSDARP00000014595.6, ENSDART00000018270.7
      Conserved Domains (2) summary
      PLN03209
      Location:281 → 444
      PLN03209; translocon at the inner envelope of chloroplast subunit 62; Provisional
      COG0124
      Location:96 → 166
      HisS; Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      55424558..55437091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166160.5 → XP_005166217.1  nuclear receptor coactivator 5 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BDI8
      Conserved Domains (2) summary
      COG0724
      Location:1 → 168
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12341
      Location:27 → 94
      RRM_hnRNPC_like; RNA recognition motif in heterogeneous nuclear ribonucleoprotein C (hnRNP C)-related proteins

    2. XM_005166161.5 → XP_005166218.1  nuclear receptor coactivator 5 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BDM6
      Conserved Domains (2) summary
      pfam08648
      Location:82 → 148
      DUF1777; Protein of unknown function (DUF1777)
      cl17169
      Location:27 → 59
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_005166162.5 → XP_005166219.1  nuclear receptor coactivator 5 isoform X3

      UniProtKB/TrEMBL
      A0A8M2BDJ5
      Conserved Domains (1) summary
      pfam08648
      Location:24 → 90
      DUF1777; Protein of unknown function (DUF1777)
    Nucleotide Protein Strain
    Heading Accession and Version

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