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    ech1 enoyl CoA hydratase 1, peroxisomal [ Danio rerio (zebrafish) ]

    Gene ID: 450048, updated on 9-Dec-2024

    Summary

    Official Symbol
    ech1provided by ZNC
    Official Full Name
    enoyl CoA hydratase 1, peroxisomalprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-170
    See related
    Ensembl:ENSDARG00000012915 AllianceGenome:ZFIN:ZDB-GENE-041010-170
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101710
    Summary
    Predicted to enable delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be active in mitochondrion. Orthologous to human ECH1 (enoyl-CoA hydratase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ech1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (6926987..6946286, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (6930190..6949489, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene myeloid ecotropic viral integration site 3 Neighboring gene serine protease 16 Neighboring gene mitochondrial ribosomal protein S22 Neighboring gene si:ch73-311h14.2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
    NP_001006068.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006068.1NP_001006068.1  delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

      See identical proteins and their annotated locations for NP_001006068.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083254
      UniProtKB/TrEMBL
      Q5XJP4
      Related
      ENSDARP00000019234.8, ENSDART00000019330.10
      Conserved Domains (1) summary
      cl23717
      Location:31298
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      6926987..6946286 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394933.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      13436..32066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)