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    cenps centromere protein S [ Danio rerio (zebrafish) ]

    Gene ID: 569270, updated on 2-Nov-2024

    Summary

    Official Symbol
    cenpsprovided by ZNC
    Official Full Name
    centromere protein Sprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080723-52
    See related
    Ensembl:ENSDARG00000070485 AllianceGenome:ZFIN:ZDB-GENE-080723-52
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    apitd1; zgc:194319
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in replication fork processing and resolution of meiotic recombination intermediates. Predicted to act upstream of or within DNA repair. Predicted to be part of FANCM-MHF complex. Orthologous to several human genes including CENPS (centromere protein S). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See cenps in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (45934724..45937000)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (45932842..45935118)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108190430 Neighboring gene hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Neighboring gene TAR DNA binding protein b Neighboring gene retinol binding protein 7b, cellular Neighboring gene carbonic anhydrase XVI b Neighboring gene CFAP20 domain containing

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in replication fork processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in resolution of meiotic recombination intermediates IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of FANCM-MHF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of FANCM-MHF complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    centromere protein S
    Names
    apoptosis-inducing, TAF9-like domain 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128749.1NP_001122221.1  centromere protein S

      See identical proteins and their annotated locations for NP_001122221.1

      Status: PROVISIONAL

      Source sequence(s)
      BC163634
      UniProtKB/TrEMBL
      B3DJV8, B3DJW6, F6NV23
      Related
      ENSDARP00000094265.2, ENSDART00000103489.4
      Conserved Domains (1) summary
      pfam15630
      Location:984
      CENP-S; Kinetochore component CENP-S

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      45934724..45937000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394666.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      31288..33564
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)