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    slc15a2 solute carrier family 15 member 2 [ Danio rerio (zebrafish) ]

    Gene ID: 556684, updated on 4-Jan-2025

    Summary

    Official Symbol
    slc15a2provided by ZNC
    Official Full Name
    solute carrier family 15 member 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5866
    See related
    Ensembl:ENSDARG00000032010 AllianceGenome:ZFIN:ZDB-GENE-030131-5866
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc84g07; wu:fi22a10; zgc:152684
    Summary
    Enables dipeptide transmembrane transporter activity. Acts upstream of or within response to yeast. Predicted to be located in phagocytic vesicle membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including gill; gut; kidney; nervous system; and otic vesicle. Orthologous to human SLC15A2 (solute carrier family 15 member 2). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See slc15a2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (37320226..37339656)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (37510431..37529861)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene inhibin subunit beta B Neighboring gene GLI family zinc finger 2a Neighboring gene hspb associated protein 1 Neighboring gene solute carrier family 49 member 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    General gene information

    Markers

    Clone Names

    • MGC152684

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables dipeptide transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables peptide:proton symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tripeptide transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in dipeptide import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dipeptide import across plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within oligopeptide transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within peptide transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidoglycan transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within response to yeast IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tripeptide import across plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in phagocytic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    solute carrier family 15 member 2
    Names
    PEPT2
    peptide transporter 2
    peptide transporter PEPT2
    solute carrier family 15 (H+/peptide transporter), member 2
    solute carrier family 15 (oligopeptide transporter), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039828.1NP_001034917.1  solute carrier family 15 member 2

      See identical proteins and their annotated locations for NP_001034917.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ192597
      UniProtKB/Swiss-Prot
      B0S6T2, Q08BT0, Q2F800
      Related
      ENSDARP00000091395.3, ENSDART00000100622.5
      Conserved Domains (2) summary
      TIGR00926
      Location:44679
      2A1704; Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
      pfam00854
      Location:97416
      PTR2; POT family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      37320226..37339656
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)