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    mis18bp1 MIS18 binding protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 368727, updated on 4-Jan-2025

    Summary

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    Official Symbol
    mis18bp1provided by ZNC
    Official Full Name
    MIS18 binding protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-151
    See related
    Ensembl:ENSDARG00000042563 AllianceGenome:ZFIN:ZDB-GENE-030616-151
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dz142b24.1; si:dkey-11j8.1; si:busm1-142b24.1
    Summary
    Predicted to be active in chromosome, centromeric region. Orthologous to human MIS18BP1 (MIS18 binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See mis18bp1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (28611745..28623360)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (28594782..28606397)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene MAM domain containing glycosylphosphatidylinositol anchor 2a Neighboring gene im:7136021 Neighboring gene HEAT repeat containing 5a Neighboring gene HECT domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A subtracted cDNA library from the zebrafish (Danio rerio) embryonic inner ear. Coimbra RS, et al. Genome Res, 2002 Jun. PMID 12045154, Free PMC Article
    2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ11186

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mis18-binding protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001312886.1 → NP_001299815.1  mis18-binding protein 1

      Status: VALIDATED

      Source sequence(s)
      BX465838
      UniProtKB/TrEMBL
      A0A8M1P808, F1RAN4
      Related
      ENSDARP00000128453.1, ENSDART00000156711.3
      Conserved Domains (4) summary
      smart00717
      Location:883 → 933
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      smart00579
      Location:951 → 979
      FBD; domain in FBox and BRCT domain containing plant proteins
      cd00167
      Location:884 → 930
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam09133
      Location:352 → 434
      SANTA; SANTA (SANT Associated)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      28611745..28623360
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005158758.5 → XP_005158815.1  mis18-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B5N0
      Conserved Domains (4) summary
      smart00717
      Location:883 → 933
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      smart00579
      Location:951 → 979
      FBD; domain in FBox and BRCT domain containing plant proteins
      cd00167
      Location:884 → 930
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam09133
      Location:352 → 434
      SANTA; SANTA (SANT Associated)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394995.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      507457..519072
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001006661.1: Suppressed sequence

      Description
      NM_001006661.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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