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    ahnak AHNAK nucleoprotein [ Danio rerio (zebrafish) ]

    Gene ID: 559276, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ahnakprovided by ZNC
    Official Full Name
    AHNAK nucleoproteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8719
    See related
    Ensembl:ENSDARG00000061764 AllianceGenome:ZFIN:ZDB-GENE-030131-8719
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb05a01; wu:fu74f12
    Summary
    Predicted to enable oxidoreductase activity. Predicted to be involved in regulation of RNA splicing. Predicted to be active in costamere and nucleus. Orthologous to several human genes including AHNAK (AHNAK nucleoprotein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ahnak in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (26759332..26796334)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (26461182..26498229)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene RNA polymerase II subunit G Neighboring gene eukaryotic translation elongation factor 1 gamma Neighboring gene kelch-like family member 4 Neighboring gene uncharacterized LOC137487526

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Regulatory significance of CULLIN2 in neuronal differentiation and regeneration. Vijayan AN, et al. Neurochem Int, 2022 Oct. PMID 35803325
    2. Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. Westcot SE, et al. PLoS One, 2015. PMID 26110643, Free PMC Article
    3. Building the vertebrate codex using the gene breaking protein trap library. Ichino N, et al. Elife, 2020 Aug 11. PMID 32779569, Free PMC Article
    4. In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish. Xiong Z, et al. Elife, 2021 Feb 16. PMID 33591275, Free PMC Article
    5. Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Leung YF, et al. Invest Ophthalmol Vis Sci, 2007 Feb. PMID 17251491, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in costamere IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    neuroblast differentiation-associated protein AHNAK

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      26759332..26796334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173182.5 → XP_005173239.1  neuroblast differentiation-associated protein AHNAK

      UniProtKB/TrEMBL
      A0A8M2BKH5, A0A8M2BKH7, A0A8M3B0A8, F1QZ50
      Related
      ENSDARP00000082917.4, ENSDART00000088484.7
      Conserved Domains (1) summary
      COG2911
      Location:1497 → 2107
      TamB; Autotransporter translocation and assembly factor TamB [Intracellular trafficking, secretion, and vesicular transport]
    Nucleotide Protein Strain
    Heading Accession and Version

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