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    Acoxl acyl-Coenzyme A oxidase-like [ Mus musculus (house mouse) ]

    Gene ID: 74121, updated on 27-Nov-2024

    Summary

    Official Symbol
    Acoxlprovided by MGI
    Official Full Name
    acyl-Coenzyme A oxidase-likeprovided by MGI
    Primary source
    MGI:MGI:1921371
    See related
    Ensembl:ENSMUSG00000027380 AllianceGenome:MGI:1921371
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1200014P05Rik
    Summary
    Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase. Predicted to be active in peroxisome. Orthologous to human ACOXL (acyl-CoA oxidase like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in lung adult (RPKM 9.6), testis adult (RPKM 1.6) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Acoxl in Genome Data Viewer
    Location:
    2 F1; 2 62.1 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (127680717..127968172)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (127838797..128126252)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E415 Neighboring gene STARR-seq mESC enhancer starr_05631 Neighboring gene mitoregulin Neighboring gene BUB1, mitotic checkpoint serine/threonine kinase Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:127753660-127754051 Neighboring gene STARR-positive B cell enhancer ABC_E7858 Neighboring gene STARR-positive B cell enhancer ABC_E9204 Neighboring gene STARR-positive B cell enhancer ABC_E10140 Neighboring gene STARR-seq mESC enhancer starr_05633 Neighboring gene STARR-positive B cell enhancer ABC_E10141 Neighboring gene STARR-positive B cell enhancer ABC_E4497 Neighboring gene STARR-positive B cell enhancer ABC_E9532 Neighboring gene STARR-positive B cell enhancer mm9_chr2:127953069-127953369 Neighboring gene STARR-seq mESC enhancer starr_05636 Neighboring gene predicted gene, 23101 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:127978569-127978830 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:127981992-127982193 Neighboring gene BCL2 like 11 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:128029897-128030080 Neighboring gene predicted gene 14009 Neighboring gene STARR-seq mESC enhancer starr_05639 Neighboring gene STARR-seq mESC enhancer starr_05640 Neighboring gene STARR-seq mESC enhancer starr_05641 Neighboring gene STARR-positive B cell enhancer ABC_E5979 Neighboring gene STARR-seq mESC enhancer starr_05642 Neighboring gene STARR-positive B cell enhancer ABC_E7860 Neighboring gene myeloid RNA regulator of BCL2L11 induced cell death Neighboring gene STARR-positive B cell enhancer ABC_E11707 Neighboring gene STARR-positive B cell enhancer ABC_E10142 Neighboring gene STARR-positive B cell enhancer ABC_E11160 Neighboring gene STARR-positive B cell enhancer mm9_chr2:128221938-128222238 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:128238239-128238556 Neighboring gene predicted gene 14010

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyl-CoA oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables acyl-CoA oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables fatty acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid beta-oxidation using acyl-CoA oxidase IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    acyl-coenzyme A oxidase-like protein
    Names
    acyl-CoA oxidase-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028765.3NP_083041.1  acyl-coenzyme A oxidase-like protein

      See identical proteins and their annotated locations for NP_083041.1

      Status: VALIDATED

      Source sequence(s)
      AK004775, BE947230
      Consensus CDS
      CCDS16711.1
      UniProtKB/Swiss-Prot
      Q80ZM1, Q9DBS4
      Related
      ENSMUSP00000028859.2, ENSMUST00000028859.8
      Conserved Domains (2) summary
      PLN02636
      Location:50599
      PLN02636; acyl-coenzyme A oxidase
      cl09933
      Location:51599
      ACAD; Acyl-CoA dehydrogenase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      127680717..127968172
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500273.2XP_006500336.1  acyl-coenzyme A oxidase-like protein isoform X1

      Conserved Domains (1) summary
      cl09933
      Location:25622
      ACAD; Acyl-CoA dehydrogenase
    2. XM_011239808.1XP_011238110.1  acyl-coenzyme A oxidase-like protein isoform X2

      See identical proteins and their annotated locations for XP_011238110.1

      UniProtKB/Swiss-Prot
      Q9DBS4
      Related
      ENSMUSP00000105973.2, ENSMUST00000110344.2
      Conserved Domains (1) summary
      cl09933
      Location:2319
      ACAD; Acyl-CoA dehydrogenase