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    KCS11 3-ketoacyl-CoA synthase 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817205, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KCS11
    Official Full Name
    3-ketoacyl-CoA synthase 11
    Primary source
    TAIR:AT2G26640
    Locus tag
    AT2G26640
    See related
    Araport:AT2G26640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-ketoacyl-CoA synthase 11; F18A8.1; F18A8_1
    Summary
    Encodes KCS11, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
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    Genomic context

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    See KCS11 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (11329719..11331858)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Pectin lyase-like superfamily protein Neighboring gene pseudo Neighboring gene K+ transporter 1 Neighboring gene SPX domain-containing protein 2 (SPX2) Neighboring gene Plant heme oxygenase (decyclizing) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tackling functional redundancy of Arabidopsis fatty acid elongase complexes. Batsale M, et al. Front Plant Sci, 2023. PMID 36798704, Free PMC Article
    2. The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling. Joubès J, et al. Plant Mol Biol, 2008 Jul. PMID 18465198
    3. Identification of proteins that interact with catalytically active calcium-dependent protein kinases from Arabidopsis. Uno Y, et al. Mol Genet Genomics, 2009 Apr. PMID 19130088
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128221.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-ketoacyl-CoA synthase 11
    NP_180232.1
    • 3-ketoacyl-CoA synthase 11 (KCS11); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity; INVOLVED IN: response to cold, response to light stimulus, response to osmotic stress; LOCATED IN: membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 2 (TAIR:AT1G04220.1); Has 3664 Blast hits to 3650 proteins in 908 species: Archae - 0; Bacteria - 1588; Metazoa - 0; Fungi - 2; Plants - 1914; Viruses - 0; Other Eukaryotes - 160 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11329719..11331858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128221.6 → NP_180232.1  3-ketoacyl-CoA synthase 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180232.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48780
      UniProtKB/TrEMBL
      A0A178VRM0, A0A5S9X1I6
      Conserved Domains (1) summary
      PLN02192
      Location:1 → 509
      PLN02192; 3-ketoacyl-CoA synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48780.1

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