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    CYP86A8 cytochrome P450, family 86, subfamily A, polypeptide 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819205, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP86A8
    Official Full Name
    cytochrome P450, family 86, subfamily A, polypeptide 8
    Primary source
    TAIR:AT2G45970
    Locus tag
    AT2G45970
    See related
    Araport:AT2G45970
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; cytochrome P450; F4I18.5; family 86; LACERATA; LCR; polypeptide 8; polypeptide 8''; subfamily A
    Summary
    Encodes a member of the CYP86A subfamily of cytochrome p450 genes. Expressed at moderate levels in flowers, leaves, roots and stems.
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    Genomic context

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    See CYP86A8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (18912095..18914739, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF295) Neighboring gene SKP1-like 20 Neighboring gene plasma membrane intrinsic protein 1B Neighboring gene mesoderm induction early response protein Neighboring gene ribosomal RNA small subunit methyltransferase G Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of the LACERATA gene of Arabidopsis provides evidence for different roles of fatty acid omega -hydroxylation in development. Wellesen K, et al. Proc Natl Acad Sci U S A, 2001 Aug 14. PMID 11493698, Free PMC Article
    2. Differential expression and evolution of the Arabidopsis CYP86A subfamily. Duan H, et al. Plant Physiol, 2005 Mar. PMID 15709153, Free PMC Article
    3. Identification of novel seed longevity genes related to oxidative stress and seed coat by genome-wide association studies and reverse genetics. Renard J, et al. Plant Cell Environ, 2020 Oct. PMID 32519347
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_130160.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alkane 1-monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aromatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within seed coat development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 86, subfamily A, polypeptide 8
    NP_182121.1
    • ''cytochrome P450, family 86, subfamily A, polypeptide 8'' (CYP86A8); FUNCTIONS IN: alkane 1-monooxygenase activity, oxygen binding; INVOLVED IN: fatty acid metabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 86, subfamily A, polypeptide 4 (TAIR:AT1G01600.1); Has 27979 Blast hits to 27896 proteins in 1493 species: Archae - 44; Bacteria - 2538; Metazoa - 10315; Fungi - 6189; Plants - 7925; Viruses - 3; Other Eukaryotes - 965 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18912095..18914739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130160.3 → NP_182121.1  cytochrome P450, family 86, subfamily A, polypeptide 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182121.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80823
      UniProtKB/TrEMBL
      A0A5S9X7C3, A0A7G2EHA1
      Conserved Domains (1) summary
      cd11064
      Location:67 → 503
      CYP86A; cytochrome P450 family 86, subfamily A
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80823.1

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