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    HAC2 histone acetyltransferase of the CBP family 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843042, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HAC2
    Official Full Name
    histone acetyltransferase of the CBP family 2
    Primary source
    TAIR:AT1G67220
    Locus tag
    AT1G67220
    See related
    Araport:AT1G67220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA P300/CBP ACETYLTRANSFERASE-RELATED PROTEIN 1; ATHPCAT1; F1N21.4; HAC02; histone acetyltransferase of the CBP family 2
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    Genomic context

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    See HAC2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (25145587..25150558)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Proline-rich spliceosome-associated (PSP) family protein / zinc knuckle (CCHC-type) family protein Neighboring gene ncRNA Neighboring gene little nuclei1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In vitro specificities of Arabidopsis co-activator histone acetyltransferases: implications for histone hyperacetylation in gene activation. Earley KW, et al. Plant J, 2007 Nov. PMID 17877703
    2. Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes. Pandey R, et al. Nucleic Acids Res, 2002 Dec 1. PMID 12466527, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    NOT enables histone acetyltransferase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    histone acetyltransferase of the CBP family 2
    NP_564891.4
    • histone acetyltransferase of the CBP family 2 (HAC2); FUNCTIONS IN: histone acetyltransferase activity, transcription cofactor activity, DNA binding; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: shoot apical meristem, root, flower, leaf; CONTAINS InterPro DOMAIN/s: Histone H3-K56 acetyltransferase, RTT109 (InterPro:IPR013178), Zinc finger, TAZ-type (InterPro:IPR000197), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, ZZ-type (InterPro:IPR000433), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: histone acetyltransferase of the CBP family 1 (TAIR:AT1G79000.1); Has 1838 Blast hits to 1436 proteins in 226 species: Archae - 0; Bacteria - 234; Metazoa - 975; Fungi - 55; Plants - 202; Viruses - 0; Other Eukaryotes - 372 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      25145587..25150558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105391.4 → NP_564891.4  histone acetyltransferase of the CBP family 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564891.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FYH1
      UniProtKB/TrEMBL
      A0A5S9WSQ6, A0A654EXH5
      Conserved Domains (5) summary
      smart00551
      Location:1275 → 1357
      ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
      cd02345
      Location:1223 → 1268
      ZZ_dah; Zinc finger, ZZ type. Zinc finger present in Drosophila dah and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dah (discontinuous actin hexagon) is a membrane associated ...
      cd15614
      Location:690 → 762
      PHD_HAC_like; PHD finger found in Arabidopsis thaliana histone acetyltransferases (HATs) HAC and similar proteins
      cl00295
      Location:1099 → 1128
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cl02120
      Location:822 → 1025
      HAT_KAT11; Histone acetylation protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FYH1.2

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